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缝隙连接阻断剂heptanol对内皮素收缩大鼠肠系膜动脉的抑制作用 被引量：1

Effect of gap junction blocker heptanol on the ET -1-induced vasoconstriction in rat mesenteric artery
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作者 蒋丽萍 韩小建 卢慧敏 洪涛
机构地区 江西医学院药理教研室 江西医学院第一附属医院神经外科
出处 《中国药理学通报》 CAS CSCD 北大核心 2004年第11期1313-1314,共2页 Chinese Pharmacological Bulletin
基金 国家自然科学基金资助项目No 3 9960 0 76
关键词 缝隙连接 缝隙连接蛋白 1-庚醇 大鼠离体肠系膜上动脉 内皮素-1 gap junction connexin heptanol rat superior mesenteric artery ET-1
分类号 R-332 [医药卫生] R322.45 [医药卫生—人体解剖和组织胚胎学]
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参考文献9

  • 1Seul KH, Beyer EC. Mouse connexin 37:gene structure and promoter analysis[J].Biochim Biophys Acta, 2000,1492(2-3):499-504.
  • 2Sosinsky GE. Molecular organization of gap junction membrane channels[J]. J Bioenerg Biomembr, 1996,28(4):297-309.
  • 3蒋丽萍,韩小建,卢慧敏,洪涛.缝隙连接在苯肾上腺素缩血管中的作用[J].中国药理学通报,2003,19(12):1358-1361. 被引量：2
  • 4Li X, Simard JM. Multiple connexins form gap junction channels in rat basilar artery smooth muscle cells[J]. Circ Res,1999,84(11):1277-84.
  • 5Severs NJ, Rothery S, Dupont E et al.Immunocytochemical analysis of connexin expression in the healthy and diseased cardiovascular system[J]. Microsc Res Tech, 2001,52(3):301-22.
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  • 7Hong T, Hill CE. Restricted expression of the gap junctional protein connexin 43 in the arterial system of the rat[J]. J Anat,1998,192(Pt 4):583-93.
  • 8Larson DM,Haudenschild CC, Beyer EC. Gap junction messenger RNA expression by vascular wall cells[J]. Circ Res,1990,66(4):1074-80.
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二级参考文献10

  • 1韩启德.肾上腺素受体研究进展[J].生理科学进展,1995,26(2):103-109. 被引量：14
  • 2Edwards G, Feletou M, Gardener MJ et al. Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol,1999;128:1788～94
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  • 4Segal SS, Duling BR. Conduction of vasomotor in arterioles: A role for cell-to-cell coupling? AM J Physiol,1989;256:838～45
  • 5Christ GJ, Spektor M, Brink BR, Barr L. Further evidence for the selective disruption of intercellular communication by heptanol. Am J Physiol,1999;276:1911～7
  • 6Chaytor AT, Martin PE, Edwards DH, Griffith TM. Gap junctional communication underpins EDHF-type relaxations evoked by ACh in the rat hepatic artery. Am J Physiol Heart Circ Physiol,2001;280(6):2441～50
  • 7Doughty JM, Boyle JP, Langton PD. Potassium does not mimic EDHF in rat mesenteric arteries. Br J Pharmacol,2000;130(5):1174～82
  • 8可君. 离体脑血管实验法. 见:徐叔云,卞如濂,陈修主编. 药理实验方法学,第3版,北京:人民卫生出版社,2002:1060-78
  • 9Hofer T, Politi A, Heinrich R. Intercellular Ca2+ wave propagation through gap-junctional Ca2+ diffusion: A theoretical study. Biophys J,2001;80(1):75～87
  • 10Quist AP, Rhee SK, Lin H, Lal R. Physiological role of gap-junctional hemichannels: Extracellular calcium-dependent isosmotic volum regulation. J Cell Biol,2000;148(5):1063～74

共引文献3

同被引文献10

  • 1Joon PH, Hyunja K. The effect of hyperbaric oxygen on ischemiareperfusion injury. Ann Plat Surg, 2003,51 (5) :478-487.
  • 2Joan C, Phillips RN. Understanding hyperbaric oxygen therapy and its use in the treatment of compromised skin grafts and flaps. Plast Surg Nurs, 2005,25 ( 2 ) :72- 80.
  • 3Richard C, Baynosa MD. The effect of hyperbaric oxygen on nitric oxide synthase and vascular endothelial growth factor expression in ischemia reperfusion injury. Plast Reconstr Surg,2004,9(1):62-65.
  • 4Ijichi H, Taketomi A, Yoshizumi T, et al. Hyperbaric oxygen induces vascular endothelial growth factor and reduces liver injury in regenerating rat liver after partial hepatectomy. J Hepatology, 2006,45( 1 ) :28-34.
  • 5Lee CC, Chen SC, Tsai SC, et al. Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells. J Biomed Sci ,2006, 13(1) :143-156.
  • 6Yang S, Graham J, Kahn JW, et al. Functional roles for PECAM-1 ( CD31 ) and VE-cadherin ( CD144 ) in tube assembly and lumen formation in three - dimensional collagengels. Am J Pathol, 1999,155:887-895.
  • 7Rhea C, Pimentel, Kathryn A, et al. Autocrine regulation of myocyte CX43 expression by VEGF. Circulation Res, 2002,90: 671-677.
  • 8韩红梅,樊景禹.大鼠表皮角化细胞Cx43表达和细胞增殖活性的关系[J].北京大学学报（医学版）,2001,33(2):113-117. 被引量：1
  • 9孙令,赵晔,王傲雪,巴东霞,贺迎霞.皮肤溃疡边缘血管内皮生长因子表达的研究[J].中华医学美学美容杂志,2001,7(3):124-126. 被引量：8
  • 10陈林生,钟竟林,马兆龙.高压氧对外伤患者皮瓣移植存活率的影响[J].中华航海医学与高气压医学杂志,2002,9(2):97-98. 被引量：15

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中国药理学通报
2004年 第11期

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