搏动性导管泵的研究与临床应用

The research and clinical application for pulsatile catheter pump

药物治疗对重症心力衰竭患者往往无效 ,只能通过机械循环支持才能存活。主动脉内球囊反搏 (IABP)是目前应用最广泛的短期辅助装置 ,辅助效果明显 ,但因辅助量太低 (1～ 1.5 L / m in)且必须依赖本身的左心室功能 ,以致有时不能充分地支持心脏。如应用辅助量较大的搏动性血泵则需行大的开胸手术插管 ,对急性缺血性心力衰竭的心脏无疑是一个损害 ,因此 ,其临床应用受到限制。搏动性导管 (PUCA)泵的作用介于 IABP和高辅助量的心室辅助装置之间 ,能起到既减轻前负荷 。

Some patients with advanced heart failure did not respond sufficie ntly to pharmacological therapy and therefore need mechanical assist to survive. The intra-aortic balloon pump(IABP) is the most widely used short-term assist d evice with a good result, but its pumping capacity of 1-1.5L/min is sometime s too low to support a severely sick heart . However, most blood pumps that gene rate higher pulsatile pump flows require major surgery of thoracotomy and cannul ation. It may cause a new trauma for the acute ischemic heart failure. Thus its clinical application is limited . The pulsatile catheter pump(PUCA pump) is a ne w device between the IABP and the ventricular assist devices that generate high flows. It not only provides the direct left ventricle unloading effect, but also augments the aortic pressure which in turn increases the coronary flow. For th ese reasons, the PUCA pump may have a prosperous future.