当前我国部分地区稳定性劳力型心绞痛治疗方式的调查

A survey of treatment patterns of stable angina pectoris in parts of China

目的 抽样调查我国部分地区稳定性劳力型心绞痛患者的人口统计学特征及治疗方式。方法 为 4周前瞻性调查 ,每研究单位入选 1 0～ 30例连续的稳定性劳力型心绞痛门诊患者参加本研究 ,在 4周调查期内随访 2次。结果 96 3例患者入选本研究 ,其中 91 0 %应用抗血小板药或抗凝药 ,90 7%应用长效硝酸酯类 ,6 8 3%应用 β受体阻滞剂 ,6 3 3%应用调脂药 ,5 1 5 %应用血管紧张素转换酶抑制剂 (ACEI) ,5 0 9%应用钙拮抗剂和 36 2 %应用曲美他嗪。在最近一次随访时 ,伴随高血压的患者血压未达目标水平 [<1 4 0 /90mmHg (1mmHg =0 1 33kPa) ]者占 86 3%,总胆固醇(TC)未达目标水平 (4 6 8mmol/L)者占 73 5 %,低密度脂蛋白胆固醇 (LDL C)未达目标水平 (2 6 0mmol/L)者占 6 5 8%。结论 虽然近年来我国在稳定性劳力型心绞痛的治疗方面基本遵循了国际上公认的指南 ,但在控制高血压和高胆固醇血症等危险因素方面仍存在较大差距。

Objective The purpose of this study is to investigate the demographic characteristics and the treatment pattern of patients with stable angina pectoris in China. Methods This was a 4week prospective cohort study. Each investigator enrolled 1030 consecutive outpatients with stable angina pectoris in this study. Patients were visited twice within four weeks. Results Nine hundred and sixty three patients were enrolled in this study, among them 91.0% patients were treated with antiplatelet or antithrombotic drugs; 90.7% with longacting nitrates; 68.3% with betablockers; 63.3% with lipid lowering drug; 51.5% with angiotensinconverting enzyme inhibitors; 50.9% with calcium channel blockers and 36.2% with trimetazidine. At the most recent visit, in 86.3% of the patients the target level of blood pressure(<140/90 mm Hg), in 73.5% the target level of total cholesterol(4.68 mmol/L), and in 65.8% the target level of LDLC(2.60 mmol/L) were not achieved. Conclusion In recent years, although we have been implementing the wellrecognized international guidelines in the treatment of stable angina pectoris, there is still a large gap in controlling the risk factors such as hypertension and hypercholesterolemia.