超声检测卵巢髓质面积与总面积的比值在多囊卵巢综合征诊断中的应用

Ultrasound criterion for the diagnosis of polycystic ovary syndrome: ovarian stroma/total area ratio

目的 探讨应用超声检测卵巢髓质面积 (S)、总面积 (A) ,计算S/A比值诊断多囊卵巢综合征 (PCOS)的价值。方法 对 5 8例PCOS不孕患者 (PCOS组 )和 6 0例有正常排卵的不孕患者 (对照组 )行阴道B超检测卵巢S、A ,计算S/A比值 ;测定黄体生成素 (LH)、卵泡刺激素 (FSH)及睾酮水平 ,计算LH/FSH比值。并对PCOS组中 32例患者行高胰岛素正葡萄糖钳夹试验 (HGCT)。结果 PCOS组患者S、A及S/A比值分别为 (1 8± 0 6 )cm2 、(5 0± 1 6 )cm2 及 0 37± 0 0 9;对照组分别为 (1 2± 0 6 )cm2 、(4 4± 1 4 )cm2 及 0 2 7± 0 0 6。PCOS组S明显高于对照组 (P <0 0 1)。LH、FSH、LH/FSH比值及睾酮水平 ,PCOS组患者分别为 (8± 4 )U/L、(5± 3)U/L、2 0± 1 2及 (3 7± 0 3)nmol/L ;对照组分别为 (6± 4 )U/L、(5± 4 )U/L、1 6± 0 7及 (2 2± 0 5 )nmol/L。PCOS组 32例患者行HGCT的结果表明 ,葡萄糖输注率低于正常参考值 ,与S、S/A比值呈明显的负相关关系。结论 S/A比值。

Objective To evaluate the diagnostic value of ultrasound parameters of ovarian stroma area(S),total ovarian area(A)and S/A ratio for polycystic ovarian syndrome(PCOS). Methods The A,S and S/A ratio were determined by use of transvaginal pelvic ultrasound, and serum levels of follicle stimulating hormone (FSH),luteinizing hormone(LH) and testosterone(T) were assayed in 58 PCOS patients and 60 controls. Of 58 PCOS patients, 32 underwent hyperinsulinemic euglycemic clamp technique (HGCT). Results Patients with PCOS showed significantly higher ovarian S and S/A ratio when compared to the control groups (P=0.045,P=0.001, respectively). S/A ratio and S were significantly related to HGCT results and T. Conclusion The S/A ratio and S are of value in diagnosis of PCOS.