卵巢颗粒细胞瘤40例临床分析

Clinical Analysis of 40 Cases of Ovarian Granulosa Cell Tumor

目的 :探讨卵巢颗粒细胞瘤的临床特点及对预后的影响因素。方法 :回顾性分析 4 0例卵巢颗粒细胞瘤患者的临床资料 ,比较不同期别、不同组织学分化程度以及不同治疗方法对预后的影响。结果 :全组总的 5年和 10年生存率分别为 95 %和 75 %。 5年和 10年存活率I期患者分别为 10 0 %和 93.1% ;II期患者分别为 88.9%和33.3% ;III期患者分别为 5 0 %和 0 ,提示 5年和 10年存活率随临床分期的增加而降低 ;病理分级越高生存率越低。I期病人应用不同治疗方法对存活率无明显影响。结论 :卵巢颗粒细胞瘤的临床分期和组织学分化程度是影响患者预后的主要因素。

Objective:?To exploe the factors related to the prognosis of granulosa cell tumor and its clinical characteristics.Methods:?40 cases of ovarian granulosa cell tumor with different stages and grades and treated with various methods were reviewed.Results:?The overall 5-and 10-year survival rates were 95% and 75%. The 5-and 10-year survival rates were 100% and 93.1% in stage Ⅰ, 88.9% and 33.3% in stage Ⅱ, 50% and 0 in stage Ⅲ. The 5-year and 10-year survival rates decreased with the increase of clinical stage and pathological grade. Different treatment methods didn't influence the survival rate of stage Ⅰ patients.Conclusion:?Tumor stage and grade are major factors to influence the prognosis of patients with granulosa cell tumor.