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P-糖蛋白在药物脑部转运中作用的研究进展 被引量:5

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出处 《中国临床药学杂志》 CAS 2004年第6期382-385,共4页 Chinese Journal of Clinical Pharmacy
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参考文献27

  • 1吴寿荣,程刚.脑靶向给药系统的研究进展[J].中国医药工业杂志,2002,33(5):247-251. 被引量:14
  • 2张喜平,金先庆,王珊,许嘉陵.小儿颅内肿瘤P-糖蛋白表达的定位检测及临床意义[J].中华神经外科杂志,2000,16(4):219-221. 被引量:8
  • 3Letrent SP, Pollack GM, Brouwer KR, et al. Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat[J]. Drug Metab Dispos,1999,27(7) :827.
  • 4Seegers U,Potschka H,Looscher W. Transient increase of P-glyeoprotein expression in endothelium and parenchyma of limbic brain regions in the kainate model of temporal lobe epilepsy[J]. Eilepsy Resarch, 2002, 51(3) :257.
  • 5Reinhardt CA, Gloor SM. Co-culture blood-brain barrier models and their use for pharmatoxicologial screening[J] .Toxicol in Vitro, 1997,11(5):513.
  • 6Zhang Y, Bachmeier C, Miller DW, In vitro and in vivo models for assessing drug efflux transporter activity[J]. Adv Drug Delivery Rev,2003,55(1) :31.
  • 7Fromm MF. The influence of MDR 1 polmyorphisms on P-glycprotein expression and function in humans[J]. Adv Drug Deliv Rev,2002,54(10): 1295.
  • 8Lin JH. Drug-drug interaction mediated by inhibition and induction of Pglycoprotein[ J]. Adv Drug Deliv Rev,2003,55(1):53.
  • 9Varma MV, Ashodraj Y, Dey CS. P-glycoprotein inhibitors and their screening:a perspective from bioavailability enhancement[J]. Pharmacological Research,2003,48(4) :347.
  • 10Dantzing AH, Alwis DPD, Burgess M. Consideration in the design and development of transport[J] ,Adv Drug Deliv Rev,2003,55(1):133.

二级参考文献37

  • 1徐伟,王宗锐.薄荷醇及冰片对磺胺嘧啶和伊文思蓝在脑中分布的影响[J].中药药理与临床,1995,11(6):31-33. 被引量:68
  • 2刘启德,梁美蓉,陈芝喜,冯美蓉,赵萍.冰片对庆大霉素透血脑屏障的影响[J].广州中医学院学报,1994,11(1):37-40. 被引量:105
  • 3田晖,潘启超.双苄基异喹啉类生物碱粉防己碱与小檗胺逆转多药抗药性的比较研究[J].药学学报,1997,32(4):245-250. 被引量:24
  • 4Basak SC,Gute BD,Drewes LR.Prediction blood-brain transport of drugs:A computation approach[J].Pharm Res,1996,13(5):775-778.
  • 5Yoshikawa T,Sakaeda T,Sugawara T,et al.A novel chemical delivery system for brain targeting[J].Adv Drug Delivery Rev,1999,36(2-3):255-275.
  • 6Tsuji A,Tamai I.Carrier-mediated or specialized transport of drugs across the blood-brain barrier[J].Adv Drug Delivery Rev,1999,36(2-3):277-290.
  • 7Chow H-HS,Chen Z,Matsuura GT.Direct transport of cocaine from the nasal cavity to the brain following intranasal cocaine administration in rats[J].J Pharm Sci,1999,88(8):754-758.
  • 8Schinkel AH.P-Glycoprotein,a gatekeeper in the blood-brain barrier[J].Adv Drug Del Rev,1999,36(2-3):179-194.
  • 9Matsuzaki J,Yamamoto C,Miyama T,et al.Contribution of P-glycoprotein to bunitrol efflux across blood-brain barrer[J].Biopharm Drug Dispos,1999,20(2):85-90.
  • 10Kawahara M,Sakata A,Miyashita T,et al.Physiologically based pharmacokinetics of digoxin mdrla knockout mice[J].J Pharm Sci,1999,88(12):1281-1287.

共引文献28

同被引文献56

  • 1何卉,陈西敬,王广基.基因敲除与基因突变动物模型在药物跨膜转运研究中的应用[J].中国药科大学学报,2005,36(6):483-487. 被引量:3
  • 2宋娟,刘晓磊,彭文兴.P-糖蛋白介导药物相互作用的细胞模型研究概况[J].中国药房,2006,17(15):1183-1185. 被引量:7
  • 3陆榕,孙进,赵春顺,何仲贵.转运蛋白在药物血脑屏障转运中的重要作用[J].中国新药与临床杂志,2007,26(1):64-71. 被引量:9
  • 4Loscher W,Potschka H.Blood-brain barrier active efflux transporters:ATP-binding cassette gene family.NeuroRx,2005,2:86-98.
  • 5Lee JY,Urbatsch IL,Senior AE,et al.Projection structure of P-glycoprotein by electron microscopy.Evidence for a closed conformation of the nucleotide binding domains.J Biol Chem,2002,277:40125-40131.
  • 6Borst P,Evers R,Kool M,et al.A family of drug transporters:the multidrug resistance-associated proteins.J Natl Cancer Inst,2000,92:1295-1302.
  • 7Lee YJ,Kusuhara H,Jonker JW,et al.Investigation of efflux transport of dehydroepiandrosterone sulfate and mitoxantrone at the mouse blood-brain barrier:a minor role of breast cancer resistance protein.J Pharmacol Exp Ther,2005,312:44-52.
  • 8Bielder JL,Reiehm H.Cellular resistance to actinomycin D in Chinese hamster cells in vitro:cross-resistance,radioautographic,and cytogenetic studies.Cancer Res,1970,30:1174-1184.
  • 9Juliano RL,Ling V.A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants.Biochim Biophys Acta,1976,455:152-162.
  • 10Cordon-Cardo C,O'Brien JP,Casals D,et al.Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.Proc Natl Acad Sci USA,1989,86:695-698.

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