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一种新型肠黏膜保护剂——肠三叶因子 被引量:2

A new intestinal mucosa protective:intestinal trefoil factor
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摘要 肠三叶因子属于三叶肽家族,是一类较新的对肠黏膜有保护作用的因子。它在肠杯状细胞大量合成,能抵抗蛋白酶的消化,且在保护肠道黏膜的完整性、促进肠黏膜损伤后的重建与修复及在肠黏液细胞的抗凋亡中有重要的作用。迄今,很多炎性肠病中都缺少有效的治疗方法,肠三叶因子的研究为肠道疾病的治疗开辟了治疗新途径。该文对肠三叶因子的结构、分布、对肠黏膜保护和修复作用可能的分子机制和调节因素作一综述。
出处 《国外医学(儿科学分册)》 2004年第6期297-299,共3页 Foreign Medical Sciences(Section of Pediatrics)
关键词 肽类 肠黏膜
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