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蛋白质组学及其在肾脏疾病中的应用 被引量：1

The proteomics and application of proteomic approach to nephropathy
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摘要 蛋白质组学作为后基因时代的一个重要内容,已广泛深入到生命科学与医药学的各个领域,其理论与技术的发展和完善为人类疾病的研究带来了新的思维方式。近年来,蛋白质组学技术应用于肾脏疾病的研究领域,通过分析尿液蛋白或肾脏组织蛋白样本,分离和鉴定出了一些有意义的蛋白质分子标志物,在研究肾脏疾病发病机制、诊断和治疗各方面展示了一些有价值的研究结果。
作者 丁娟娟 何庆南
机构地区 中南大学湘雅二医院儿科
出处 《国外医学（儿科学分册）》 2004年第6期312-314,共3页 Foreign Medical Sciences（Section of Pediatrics)
关键词 蛋白质组 凝胶 电泳 光谱分析 质量 肾疾病
分类号 R692 [医药卫生—泌尿科学]
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参考文献12

  • 1Cutillas PR, Norden AG, Cramer R, et al. Detection and analysis of urinary peptides by on-line liquid chromatography and mass spectrometry: application to patients with renal Fanconi syndrome [J].Clin Sci (Lond),2003, 104(5) :483-490.
  • 2Candiano G,Musante L,Carraro M,et al. Apolipoproteins prevent glomerular albumin permeability induced in vitro by serum from patients with focal segmental glomerulosclerosis[J]. J Am Soc Nephrol,2001, 12(1): 143-150.
  • 3Kiernan UA,Tubbs KA,Nedelkov D,et al. Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay [J]. Biochem Biophys Res Commun, 2002,297 (2): 401-405.
  • 4Pandey A, Mann M. Proteomics to study genes and genomes [J]. Nature,2000,405(6788) :837-846.
  • 5Clarke W, Silverman BC, Zhang Z, et al. Characterization of renal allograft rejection by urinary proteomic analysis [J]. Ann Surg, 2003,237(5) :660-664.
  • 6Aicher L, Wahl D, Arce A, et al. New insights into cyclosporine A nephrotoxicity by proteome analysis [J]. Electrophoresis, 1998, 19 (11):1998-2003.
  • 7HiKi Y, Odani H, Takahashi M, et al. Mass spectrometry proves under-Oglycosylation of glomerular IgA1 in IgA nephropathy[J]. Kidney Int,2001,59(3): 1077-1085.
  • 8Musante L, Candiano G, Bruschi M, et al. Characterization of plasma factors that alter the permeability to albumin within isolated glomeruli [J].Proteomics,2002,2(2): 197-205.
  • 9Nourooz-Zadeh J, Pereira P.F(2)isoprostanes,potential specific markers of oxidative damage in human retina[J]. Ophthalmic Res, 2000,32(4): 133-137.
  • 10Sarto C,Deon C, Doro G, et al. Contribution of proteomics to the molecular analysis of renal cell carcinoma with an emphasis on manganese superoxide dismutese[J]. Proteomics, 2001,1 (10): 1288-1294.

同被引文献34

  • 1罗治文 ,朱樑 ,谢渭芬 .质谱技术研究进展[J].国外医学（生物医学工程分册）,2005,28(3):134-137. 被引量：11
  • 2Soulages J L,Kim K,Walters C,et al.Temperature-induced extended helix/random coil transitions in a group 1 late embryogenesis-abundant protein from soybean[J].Plant Physiol,2002,128:822-832.
  • 3Sobhanian H,Razavizadeh R,Nanjo Y,et al.Proteome analysis of soybean leaves,hypocotyls and roots under salt stress[J].Proteome Science,2010(8):1-15.
  • 4Yang H,Huang Y P,Zhi H J,et al.Proteomics-based analysis of novel genes involved in response toward soybean mosaic virus infection[J].Mol Biol Rep,2010,DOI 10.1007/sl 1033-010-0135-x.
  • 5Arai Y,Hayashi M,Nishimura M.Proteomic analysis of highly purified peroxisornes from etiolated soybean cotyledons[J].Plant Cell Physiol,2008,49:52ti-39.
  • 6Natarajan S,Xu C,Bae H,et al.Characterization of storage proteins in wild(Glycine soja)and cultivated(Glycine max)soybean seeds using proteomic analysis[J].J Agric Food Chem,2006,54:3114-3120.
  • 7Natarajan S S,Xu C,Bae H,et al.Proteomic and genetic analysis of glycinin subunits of sixteen soybean genotypes[J].Plant Physiology and Biochemistry,2007.45:436-444.
  • 8Toorchi M,Nouri M Z,Tsumura M,et al.Acoustic technology for high-performance disruption and extraction of plant proteins[J].J Proteome Res,2008(7):3035-3041.
  • 9Padgette S R,Taylor N B,Nida D L,et al.The composition of glyphosate-tolerant soybean seeds is equivalent to that of conventional soybeans[J].J Nutr,1996,126:702-716.
  • 10Buttery B R,Buzzell R I.Soybean flavonol glycosides:Identification and biochemical genetics[J].Can J Bot,1973,53:309-313.

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国外医学（儿科学分册）
2004年 第6期

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