替硝唑注射液的细菌内毒素检测

Bacterial Endotoxin Test for Tinidazole Injection

目的 :建立替硝唑注射液细菌内毒素检测方法。方法 :应用不同厂家鲎试剂对替硝唑注射液进行干扰实验。结果 :替硝唑注射液 2倍稀释液对细菌内毒素不产生干扰。结论 :细菌内毒素检测方法可取代替硝唑注射液热原的检查。

Objective: To establish a bacterial endotoxins test for tinidazole injection. Method: Interference tests in tinidazole injection were performed with limulus test agents provided by different factories. Result: Tinidazole injection diluted up to 2 times did not interfere with bacterial endotoxins.Conclusion: The bacterial endotoxins test can be used instead of pyrogen test for tinidazole injection.