摘要
本实验将60只豚鼠分为致石饲料组和普通饲料组,再将每组分为对照组和发热组。通过间断皮下注射煮沸牛奶使发热组动物发热,每周1次,共4次。45天后将全部动物处死,检查胆囊腔并取肝组织和胆汁进行分析。结果,4组动物中致石饲料发热组结石发生率最高,为40%,发热组胆汁总蛋白及胆红素浓度较对照组明显升高。发热组肝组织β—葡萄糖醛酸酶活性增强,由此我们认为,发热在胆石形成中起重要作用。
Sixty guinea pigs were divided into lithogenic and normal dietgroups,and each group was further divided into control and fever groups.Theanimals in the fever groups were injected subcutaneously with boiled milk,once a week for four times to run fever.After 45 days all the animals Were kil-led,their gallbladder lumens Were inspected and the liver and bile samplesanalyzed.The gallstone incidence of the fever group fed with lithogenic dietwas the highest,accounting for 40%(6/15).All the animals in the fevergroups had significantly higher concentration of total bile protein and bilirubin.The liverβ—glucuronidase activity in the fever groups was higher,than ot-her group.As a result we think that fever plays an important role in gallst-one formation in guinea pigs.
出处
《济宁医学院学报》
1993年第4期15-17,共3页
Journal of Jining Medical University
关键词
色素胆石
成因
发热
Pigment gallstone
Etiology
Fever
