中药对急性耐力运动大鼠脑内儿茶酚胺类神经递质的影响

Influence of Chinese Herb on Catecholamine Neurotransmitters in Different Brain Region in Rat After Acute Endurance Exercise

目的 :为中医药、单胺类神经递质与运动性中枢疲劳的研究提供依据 ;方法 :以大鼠端脑和间脑NE、DA、DOPAC等为研究指标 ,探讨补充中药对急性耐力运动大鼠脑内儿茶酚胺类神经递质的影响 ;结果 :①长时间急性耐力运动使端脑和间脑DA水平降低 ;服药组大鼠运动后端脑DA含量的增加 ,可能对维持锥体外系的功能具有积极性作用 ;间脑DA水平提高对垂体激素的释放产生何种影响 ?有待深入研究。②长时间急性耐力运动可能会对实验动物脑循环状况、学习记忆能力及精神活动等方面产生不利影响 ;中药补剂对急性耐力运动后脑循环调节、阳性条件反射的建立与执行及精神活动具有一定的积极性调节作用。③中药对耐力运动鼠端脑和间脑DA的合成和分解代谢有一定的积极性调节作用。

Study the purpose : Offer the basis for the research of using chinese herb to postpone or dispels the centre fatigue of movement quality .The research approach: With heavy for mouse for end brain, among do indexes, such as NE, DA, DOPAC,etc. from research object at brains, brains, Probe into and supplement the traditional Chinese medicine to the sport big mouse's phenol nerve influence of passing the quality of amine type of Acacia catechu in the district of different brains of acute endurance. The result of study: ① The acute endurance sport exerts a different influence on DA's level in the district of different brains for a long time; It takes medicine group heavy mouse sport back end brain DA the increases of contents might have been to keeping awl have enthusiasm function by function who body tie, Among raise produce influence at a certain enthusiasm at brain DA levels. ②The acute endurance sport may exert an unfavorable influence on the circulation state of brain of animal used as test, respects, such as memory ability and spiritual activity,etc. of studying for a long time; Traditional Chinese medicine mend circulation regulate, and and spiritual activity have sure enthusiasm regulating action execution positive the setting-ups of conditioned reflexes between pharmaceutical and acute endurance sport hindbrains by nutrition.③There may be different regulating action in catabolism of traditional Chinese medicine to different brain district DA of mouse of sport.