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脉压对心脑血管疾病的预报价值 被引量：5

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摘要 脉压(pulse pressure,PP)升高被越来越多的研究证实是心脑血管疾病,特别是冠脉疾病的危险因素,通常评价血压状况的4种血压测量指标是指收缩压(SBP)、舒张压(DBP)、PP和平均血压(MBP)[1,2].PP值为SBP与DBP之差,PP差增大说明大动脉血管顺应性降低,僵硬度增加,是反映血管壁厚/管腔直径比值的一个有意义的指标,因此,PP升高可增加心、脑血管疾病的危险,是冠心病(CHD)、脑卒中及左心室肥厚(LVH)等发生的有力指征,PP的测量包括常规的肱动脉血压计、动态血压监测、内动脉压记录和特殊部位的测量等.PP的作用独立于其他血压测量值,特别是MBP.临床医生和保健医生多习惯看到SBP的重要性,特别是老年人,但最近的流行病学研究强调了PP作为老年人心脑血管事件预报因子的重要性[3].
作者 关德明
机构地区 哈尔滨医科大学第一临床医学院心血管病研究所
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2004年第8期723-725,共3页 Chinese Journal of Epidemiology
关键词 脉压 心脑血管疾病 预报 影响因素
分类号 R54 [医药卫生—心血管疾病] R743 [医药卫生—神经病学与精神病学]
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参考文献15

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共引文献1

同被引文献38

  • 1Schulz R, Grebem M, Eisele HJ,et al. Obstructive sleep apnea - related cardiovascular disease. Med Klin (Munich), 2006,101 (4) :321-327.
  • 2Ohayon MM,Guille minaut C,Priest RG,et al. Is sleep disordered breathing an independent risk factory for hypertension in the general population( 13,057 subject) ? J Psychosom Res, 2000,48 (6):593-601.
  • 3Grote L, Hedne J, Peter J H. Mean blood pressure, pulse pressure and grade of hypertension in unt reated hypertension. Patients with sleep-related breat hing disord. J Hypertens, 2001,19 (4): 683-690.
  • 4Domanski M J, Davis B R , Pfeffor MA,et at. Isolated systolic hypertension prognostic information provided by pulse pressure. Hypertension,1999,34 (3) :375-380.
  • 5Chae CU, Pfeffor MA, Glynn R J, et al. Increased pulse pressure and risk of heart failure in the elderly. J AMA,1999,281(7):634-639.
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  • 7Lavie P, Silverberg D, Okserberg A, et al. Obstructive sleep apnea - hypopnea and hypertension: from correlative to causative relationship. J Clin Hypertension,2001, 3(5):296-301.
  • 8Imadojemu VA, Gleeson K, Quraishi SA, et al. Impaired vasodilator responses in obstructive sleep apnea are improved with continuous positive airway pressure therapy. Am J Respir Crit Care Med, 2002, 16(5) : 950-953.
  • 9Madin K, Iqbal P. Twenty-four hour ambulatory blood pressure monito-ring: a new tool for determining cardiovascular prognosis. Postgrad Med J, 2006, 82 (971):548-551.
  • 10Robinson GV, Stradling JR, Davies RJ. Sleep. 6: obstructive sleep apnoea/hypopnoea syndrome and hypertension. Thorax, 2004, 59(12): 1089 - 1094.

引证文献5

二级引证文献3

中华流行病学杂志
2004年 第8期

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