Sp1/Krüppel样转录因子家族研究进展
被引量:1
摘要
Spl/Kruppel样转录因子(Spl-like and Kruppel-like tran- scription factors,Spl/KLFs)是参与真核细胞转录的高度相关锌指蛋白,以细胞和启动子特异性方式通过调控富含GC启动子的基因表达,参与调节细胞功能如细胞增生、凋亡、分化和肿瘤形成.
出处
《世界华人消化杂志》
CAS
2004年第7期1641-1645,共5页
World Chinese Journal of Digestology
参考文献42
-
1Turner J, Crossley M. Mammalian KriippeMike transcription factors: more than just a pretty finger. Trends Biochem Sci 1999;24:236-240.
-
2Black AR, Black JD, Azizkhan-Clifford J. Spl and Kriippellike factor family of transcription factors in cell growth regulation and cancer. J Cell Physiol 2001;188:143-160.
-
3Dang DT, Pevsner J, Yang VW. The biology of the mammalian KriippeMike family of transcription factors. Int J Biochem Cell Biol 2000;32:1103-1121.
-
4Bieker JJ. Kriippel-like factors: three Fingers in many pies. J Biol Chem 2001;276:34355-34358.
-
5rCook T, Gebelein B, Urrutia R. Spl and its likes: biochemical and functional predictions for a growing family of zinc finger transcription factors. Ann NY Acad Sci 1999;880:94-102.
-
6Philipsen S, Suske G. A tale of three fingers: the family of mammalian Sp/XKLF transcription factors. Nucleic Acids Res 1999;27:2991-3000.
-
7Suske G. The Sp-family of transcription factors. Gene 1999;238:291-300.
-
8Ossipova O, Stick R, Pieler T. XSPR-1 and XSPR-2, novel Spl related zinc finger containing genes, are dynamically expressed during Xenopus embryogenesis. Mech Dev 2002;115:117-122.
-
9Schock F, Purnell BAI V~immer EA, Jackle H. Common and diverged functions of the Drosophila gene pair D-Spl and buttonhead. Mech Dev 1999;89:125-132.
-
10Oates AC, Pratt SJ, Vail B, Yan YL, Ho RK, Johnson SL,Postlethwait JH, Zon LI. The zebrafish klf gene family. Blood 2001;98:1792-1801.
同被引文献11
-
1Bradford MM. A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding[J]. Anal Biochem,1976,72(5):248-254
-
2Artlett CM, Chen SJ, Varga J, et al. Modulation of basal expression of the human alpha 1 (Ⅰ) procollagen gene (COL1A1) by tandem NF-1/Sp1 promoter elements in normal human dermal fibroblasts[J]. Matrix Biol,1998,17(6):425-434
-
3Nirodi CS, Devalaraja R, Nanney LB, et al. Chemokine and chemokine receptor expression in keloid and normal fibroblasts[J]. Wound Repair Regen,2000,8(5):371-382
-
4Haase M,Geyer P, Appold S, et al. Down-regulation of SP1 DNA binding activity in the process of radiation-induced pulmonary fibrosis[J]. Int J Radiat Biol,2000,76(4):487-492
-
5Buttner C, Skupin A, Rieber EP. Transcriptional activation of the type Ⅰ collagen genes COL1A1 and COL1A2 in fibroblasts by interleukin-4: analysis of the functional collagen promoter sequences[J]. J Cell Physiol,2004,198(2):248-258
-
6Cicchillitti L, Jimenez SA, Sala A, et al. B-Myb acts as a repressor of human COL1A1 collagen gene expression by interacting with Sp1 and CBF factors in scleroderma fibroblasts[J]. Biochem J,2004,378(Pt 2):609-616
-
7McKenna MJ, Nguyen-Huynh AT, Kristiansen AG. Association of otosclerosis with Sp1 binding site polymorphism in COL1A1 gene:evidence for a shared genetic etiology with osteoporosis[J]. Otol Neurotol,2004,25(4):447-450
-
8Rippe RA, Almounajed G, Brenner DA. Sp1 binding activity increases in activated Ito cells[J]. Hepatology,1995,22(1):241-251
-
9Leroy V, Monier F, Bottari S, et al. Circulating matrix metalloproteinases 1, 2, 9 and their inhibitors TIMP-1 and TIMP-2 as serum markers of liver fibrosis in patients with chronic hepatitis C: comparison with PIIINP and hyaluronic acid[J]. Am J Gastroenterol,2004,99(2):271-279
-
10Lee M, Song SU, Ryu JK, et al. Sp1-dependent regulation of the tissue inhibitor of metalloproteinases-1 promoter[J]. J Cell Biochem,2004,91(6):1260-1268
-
1曾彬彬,蔡兴东,刘升明.Krüppel样转录因子与人类肺癌关系的研究进展[J].内科,2016,11(2):199-202.
-
2成撒诺,李甲初,张幸平.Krüpple样转录因子8在恶性肿瘤中的研究进展[J].重庆医学,2015,44(13):1849-1851. 被引量:1
-
3贾炜.Bcl-2家族研究进展[J].当代医学,2012,18(3):26-28. 被引量:25
-
4宋尔霖,张旭.人Krüppel样因子4与肿瘤关系的研究进展[J].国际遗传学杂志,2013,36(2):56-59. 被引量:1
-
5郑乐,李天人,郭科军.KLFs与肿瘤发生发展的关系[J].解剖科学进展,2014,20(6):585-587. 被引量:1
-
6王丽杰,史晓宇,周建华.转录因子Sp1及其与肿瘤的关系[J].实用肿瘤学杂志,2008,22(5):478-480. 被引量:5
-
7邢细红,王雄伟.LRIG1基因与肿瘤关系的研究进展[J].重庆医学,2011,40(11):1120-1122. 被引量:2
-
8董笑,李琦.转录因子Klfs家族影响肝细胞癌发生发展的机制研究进展[J].中国肿瘤临床,2016,43(8):348-351. 被引量:3
-
9邹远康,李天,温博,李国印,贾林涛,王磊.蛋白激酶AKT不同亚型影响乳腺癌恶性表型的研究进展[J].现代生物医学进展,2016,16(21):4165-4169. 被引量:9
-
10马国燕,卢静.Krüppel样因子4基因表达调控的研究进展[J].中国老年学杂志,2013,33(10):2474-2477. 被引量:1