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乙型肝炎病毒DNA YMDD变异的检测技术 被引量:2

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摘要 拉米夫定治疗乙型肝炎耐药性的产生主要与HBV P基因突变有关,耐药株中多见P基因变异且相对集中于YMDD基序.YMDD变异的检测技术包括核苷酸序列测定法、聚合酶链反应-限制性片段长度多态性分析、基因芯片技术、聚合酶链反应微板核酸杂交-酶联免疫黏附法等.本文就乙型肝炎病毒DNA YMDD变异的检测技术作一综述.
出处 《世界华人消化杂志》 CAS 2004年第7期1674-1677,共4页 World Chinese Journal of Digestology
基金 国家自然科学基金攻关项目 No.C03011402.No.C30070689军队"九 五"科技攻关项目 No.98D063军队回国留学人员启动基金项目 No 98H038军队"十 五"科技攻关青年基金项目 No.01Q138军队"十 五"科技攻关面上项目 No 01MB135
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