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慢性胃炎患者临床症状与幽门螺杆菌感染的相关性 被引量:1

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摘要 目的:探讨成人上腹不适症状与H pylori感染的相关性方法:有上腹不适症状,经胃镜检查诊断为慢性胃炎的患者533例,近1 mo内未服用抗菌药物,行13C尿素呼气试验(13C-UBT)检测H pylori感染情况,观察H pylori感染与慢性胃炎临床症状之间的关系.对H pylori感染阳性并接受正规抗H pylori治疗及随访的158例患者,观察治疗前后的临床症状变化. 结果:在533例患者中H pylori阳性者286例,阳性率53.7%. H pylori阳性患者中腹痛、腹胀、反酸或烧心、嗳气、食欲差和其他症状的发生率分别为44.8%,42.3%,40.2%, 23.4%,7.7%和20.3%;而H pylori阴性患者上述症状的发生率分别为38.9%,35.6%,23.9%,23.9%,4.9%和16.2%. 除反酸烧心症状与H pylori感染相关(P<0.05)外,其余症状与是否有H pylori感染差异无显著性.反酸烧心症状在H pylori被根除后,有73.3%的患者症状好转或消失,与未被根除者之间差异有显著性(P<0.05).同时在H pylori被根除后,其余症状改善率在H pylori被根除和未被根除比较,差异无显著性(P>0.05) 结论:成人H pylori感染者反酸烧心症状发生率明显高于无H pylori感染者,抗H pylori治疗则有助于症状的缓解.
作者 李园 吴本俨
出处 《世界华人消化杂志》 CAS 2004年第7期1751-1753,共3页 World Chinese Journal of Digestology
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参考文献19

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二级参考文献49

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