摘要
我们回顾性地研究了1119例乙肝肝硬化患者(其中包括400例乙肝肝硬化肝癌患者)的各种细菌感染的发生率。探讨乙肝肝硬化细菌感染的流行病学。结果显示肝硬化病人的细菌感染率为15.4%,与肝硬化肝癌病人的细菌感染率15.3%相近,当肝硬化程度按 Child-Pugh 分级时,肝硬化病人 A 级感染率为2.3%,B 级为8.0%,C级为26.4%;肝硬化肝癌病人 A 级感染率为3.3%,B 级为11.1%,C 级为31.2%。随着肝硬化程度的增加,细菌感染率越高,严重的细菌感染发生在 B 级和 C 级患者。说明乙肝肝硬化病人的细菌感染率主要与肝硬化有关,与肝癌关系不大。
To study the prevalence of bacterial infection in hepatitis B cirrhosis,we have in- vestigated retrospectively 1119 cirrhotic patients associated with hepatitis B(including 400 hepati- tis B cirrhotic patients with hepatocellular carcinoma) for bacterial infection.The results showed that 15.4% of 719 patients with hepatitis B cirrhosis was found to have bacterial infection that was approximately equal to the percentage 15.3 of bacterial infections in 400 hepatitis B cirrhosis patients with hepatocellular carcinoma(HCC).When the severity of cirrhosis was graded accord- ing to Child-Pugh classification(A,B,and C),the infective rate was 2.3% in A,8.0% in B and 26.4% in C,in cirrhosis,and 3.3%,11.1%,and 31.2% respectively in cirrhosis with hepatocellu- lar carcinoma(HCC).The incidence of bacterial infection increased with the severity of cirrhosis and severe bacterial infection occurred in Child-Pugh class B and C.All data indicate that the sus- ceptibility of schistosomiasis cirrhosis patients to bacterial infection is mainly related to the under- lying cirrhosis and not to the HCC.
