摘要
将 1 2 0只SPF雏鸡用鸡包涵体肝炎病毒攻毒后 ,分别在 1 ,3,5,7,9,1 2 ,1 5日龄和 2 0日龄各取 1 0只 ,心脏采抗凝血 ,进行红细胞记数、血红蛋白测定 ,放血处死 ,剖检并取骨髓进行病理组织学检验。同时用 1 2 0只SPF雏鸡作空白对照。结果表明 :攻毒组鸡的红细胞和血红蛋白含量变化高度一致 ,前 5d显著高于对照 ,第 1次病毒血症时期的第 7天低于对照 ,第 2次病毒血症时高于对照。在鸡包涵体肝炎发病过程中 ,红细胞和血红蛋白由于受到刺激或损伤 ,有可能在不同程度上参与了机体的免疫反应 ,从而使红细胞和血红蛋白在攻毒后一定时期内在机体内含量有一定变化。早期骨髓细胞变性坏死 ,被脂肪细胞代替 ,7日龄时达到高峰。于2 0日龄时 。
In order to learn regulation of erythrocyte and hemoglobin in inclusion body hepatitis, 2-day-old SPF chickens were inoculated with FAV-Ⅷ and killed to take blood in 1, 3, 5,7, 9, 12, 15,20 days of post inoculation(dpi), respectively. Erythrocyte and hemoglobin were checked by autoanalyzing machine of blood in above days, respectively. The result showed: erythrocyte and hemoglobin increased significantly in 1-5 dpi;and decreased in 7 days and increased in 12 dpi; they demonstrated erythrocyte and hemoglobin not only activated or damaged, also may take part in immunological activity.
出处
《动物医学进展》
CSCD
2004年第6期108-109,共2页
Progress In Veterinary Medicine
基金
国家自然基金资助项目 (30 1 6 0 0 6 7)
