毫米波对周围神经损伤修复的影响

Experimental study of the effect of millimeter wave irradiation on the repair of peripheral injured nerve

目的 探讨毫米波对周围神经损伤修复的影响。方法 将 3 6只SD雄性大白鼠制作成左侧坐骨神经钳夹伤模型 ,随机分为治疗组和对照组。治疗组在神经损伤 2 4h后 ,用毫米波辐射损伤部位 ,每周 5次 ,每次 3 0min ,从运动功能、电生理、组织学等方面观察其对大鼠坐骨神经损伤修复的影响。结果 治疗组在术后 2 ,4,6周的运动神经传导速度均显著高于对照组 ;运动功能恢复时间明显短于对照组 ;电镜观察显示 ,对照组在术后 2周的神经变性程度比治疗组严重 ,治疗组在术后 4周和 6周的神经再生数目和成熟度均优于对照组。结论 毫米波能够促进周围神经损伤的修复和功能恢复。

Objective To investigate the influence of the millimeter wave on the repair of injured peripheral nerve. Methods The left sciatic nerves of 36 SD adult rats weighted around 220g were crushed with forceps to establish the experimental animal models of peripheral nerve injury. Then they were equally divided into a treatment group and a control group. The treatment group received millimeter wave irradiation 30 minutes a day, 5 times a week, while the control group received sham millimeter wave irradiation. At various stages after operation, the motor function scale, the sciatic nerve conduction velocity and its histologic manifestations of the two groups were detected. Results It was shown that statistical significant difference existed in terms of the recovery of nerve conduction velocity and motor function scale between the two groups. The nerve degeneration of the control group was worse than that of the treatment group two weeks after operation. The Schwann's cell proliferation, myelin recovery of the treatment group were all better than those of the control group at 4 and 6 weeks after operation. Conclusion The study suggests that the millimeter wave irradiation could promote the regeneration of peripheral nerve injury and functional recovery of the animals.