相转移催化合成1-环己基吖丁啶-3-基取代苄基醚

Synthesis of 1-cyclohexyl-3-hydroxylazeridin-3-yl substituted benzyl ethers under PTC

在相转移催化条件下合成了1 环己基吖丁啶 3 基取代苄基醚这类具有潜在生理活性的新化合物,该法操作简便,收率高,经1HNMR、IR、MS确认了产物的结构,同时讨论了合成这类化合物的最佳反应条件.

A series of 1-cyclohexylazeridin-3-yl substituted benzyl ethers, which have potential biological activities were synthesized by using PTC method. The products were identified by 1H NMR,IR and MS spectra.