陈旧性心肌梗死患者颈动脉粥样硬化与危险因素的关系

Carotid Atherosclerosis in Patients with Old Myocardial Infarction and Related Risk Factors of Cardiovascular Disease

为探讨陈旧性心肌梗死患者颈动脉粥样硬化情况,对38例陈旧性心肌梗死患者的颈动脉内中膜厚度及斑块进行超声检测,与32例健康者作对照。结果发现,陈旧性心肌梗死患者的颈动脉内中膜厚度、斑块指数及斑块发生率明显高于对照组。多因素回归分析显示,年龄、总胆固醇、收缩压与颈动脉内中膜厚度密切相关。

Aim To investigate carotid atherosclerosis in patients with old myocardial infarction and related risk factors of cardiovascular disease. Methods The plaque index and carotid intima-media thickness (IMT) were detected by high-resolution ultrasound technique in 38 patients with old myocardial infarction and 32 matched healthy controls. Results The patients with old myocardial infarction had obviously abnormal plaque index (3.47 ± 1.26 vs 0.35 ± 0.86, P<0.01) and IMT (1.04± 0.17 mm vs 0.63±0.25 mm, P<0.01) compared with the healthy controls. The prevalence rates of atherosclerotic plaques were 84.21% (32/38) and 18.75% (6/32), there was significant difference between the two groups ( P < 0.01). Multiple regression analyses showed that IMT was closely associated with age, total cholesterol and the status of hypertension. Conclusions The patients with old myocardial infarction had abnormal plaque index and IMT, there was close relationship between carotid and atherosclerosis. Carotid ultrasounic examination could help to predict the presence of coronary artery disease.