摘要
多环芳烃是一种常见的有机污染物,也是目前国际上关注的一类持久性有机污染物。其致毒机理研究是环境科学研究领域的热点问题之一,而反映暴露剂量与生物效应的生物标记物的研究是环境致癌物风险评价的核心内容。本文综述多环芳烃的暴露途径、环境行为、毒理效应、致癌机理及其生物标志物在环境风险评价中的应用,并对今后的研究内容进行讨论.
s:Polycyclic romatic hydrocarbons(PAHs )are common persistent organic pollUtants(POPs ).Thecarcinogenic mechanism of PAHs becomes one of the study hotspots in the environmental science field.Biomarkers indicting exposure dose and biological effect are esseential cotent in the assessmet ofenvironmental carcinogen.The exposure mode,fate in the environment ,toxic effect,carcinogenicmechanism and application of biomarkrs in the environmental risk assessment of PAHs is reviewed inthis paper,and propects for research on PAHs are also discussed.
出处
《河南预防医学杂志》
2003年第6期370-374,共5页
Henan Journal of Preventive Medicine