皮肤念珠菌性肉芽肿合并念珠菌性颈淋巴结炎1例

Skin candidal granuloma complicated by candidal cervical lymphadenitis: a case report

报告皮肤念珠菌性肉芽肿合并念珠菌性颈淋巴结炎1例。患者女,27岁。面部增生性红斑5年,颈部淋巴结肿大2个月。取面部皮损、咽部黏膜及颈部淋巴结进行培养,鉴定为白念珠菌生长。组织病理检查示皮肤念珠菌性肉芽肿、念珠菌性淋巴结炎。流式细胞仪检查发现患者细胞免疫功能低下。采用氟康唑静脉滴注,同时使用胸腺肽,并口服特比萘芬,治疗2个月,患者面部皮损明显改善,颈部淋巴结缩小。

The patient was a 27-year -old woman, and had proliferative lesions on the face for five years and swelling cervical lymph nodes for 2 months. Candida albicans was isolated from the lesions. the biopsy specimen of the swelling lymph node revealed budding spores and pseudohyphae. Lymphopenia with a proportionate decrease of T-helper and T-suppressor cells was shown with flow cytometry. The patient received a combination therapy of fluconazole, thymosin and so on. After two months, the granuloma condition on the patient's face was greatly improved. Many small lymph nodes disappeared and large lymph nodes became smaller.