息肉状脉络膜血管病变

Polypoidal choroidal vasculopathy

目的 观察国人息肉状脉络膜血管病变 (polypoidal choroidal vasculopathy,PCV)的眼底和血管造影特征。 方法 对 9例 PCV患者进行眼底检查、荧光素眼底血管造影 (fundus fluorescein angiog-raphy,FFA)和吲哚青绿血管造影 (indocyanine green angiography,ICGA)检查。 结果 9例患者均为单眼患病。 7例患者具有脉络膜分支状血管网及血管末端息肉状膨大 ;2例患者血管网不明显 ,但息肉状膨大明显可见。7只眼伴有出血性视网膜色素上皮 (retinal pigmentepithelium,RPE)脱离 ,其中 4只眼可见血和血浆的分界线。眼底病变部位在黄斑部者 8例 ,视盘旁者 1例。 结论 国人 PCV患者大部分有脉络膜异常分支血管网 ,所有病例均有血管末端扩张呈息肉样灶 ;病变部位以黄斑部为主 ,大多合并有出血性 RPE脱离。

Objective To observe the clinical features of polypoidal choroidal vasculopathy (PCV) in Chinese patients. Methods Nine cases (9 eyes) were examined with fundus examination, fundus fluorescein angiography (FFA) and indocyanine green angiography angiography (ICGA). Results FFA and ICGA showed the branching vascular networks (7 cases) and polyplike dilation at terminals of branches (9 cases), which mainly located in macular area (8 cases) and in peripapillary area (1 case), and which accompanied hemorrhagic or serous pigment epithelial detachment in 7 cases,and 4 of 7 cases had a significant horizontal black-white damarcation line. It definitely differed from fine choroidal neo-vascularization (CNV). Conclusion PCV in Chinese patients has the cardinal clinical features, i.e., polyplike lesions located mainly in macular area and most cases accompanied by hemorrhagic or serous pigment epithelium detachment.