大鼠胸腺的神经分布——银染色和乙酰胆碱酯酶组织化学的研究

INNERVATION IN THE RAT THYMUS——AN INVESTIGATION BY SILVER STAIN AND ACETYLCHOLINESTERASE HISTOCHEMICAL METHOD

用银染色法和乙酰胆碱酯酶(AChE)组织化学法,观察大鼠胸腺的神经纤维分布。银染色法显示,在胸腺髓质中神经纤维构成复杂的网络状结构。在胸腺皮质和髓质中,均存在AChE阳性神经纤维,其分支终止或环绕于胸腺细胞的附近。此外,AChE阳性神经纤维与肥大细胞可形成紧密邻接。有些肥大细胞含有AChE阳性反应物。作者认为,胸腺皮质和髓质都接受副交感的胆碱能神经纤维的支配,后者对胸腺细胞和肥大细胞等可能起调节作用。

The innervation in the thymus was observed by silver stain and acetylcho linesterase (AChE) histochemical method. It was shown by silver stain that nerve fibers constituted a complex network in the thymic medulla. In the cortex and medulla there were AChE-containing nerve fibers. which terminated near or encircled the thymocytes. AChE-containing nerve fibers contacted with mast cells. Some mast cells had AChE-containing substance. This study suggests that the cortex and medulla of thymus are innervated by parasympathetic cholinergic nerve fibers, which may regulate the thymocytes and mast cells.