北京鸭腔上囊不同发育阶段B细胞内肌动蛋白聚合状态的变化

STATE OF ACTIN POLYMERIZATION IN B LYMPHOCYTES FROM DIFFERENT DEVELOPMENT STAGES OF BURSA OF FABRICIUS OF PEKING DUCK

研究北京鸭腔上囊发育过程中B细胞系内肌动蛋白聚合状态的变化。结果表明,26d龄胚和出生后3周龄的腔上囊B细胞中,肌动蛋白主要以聚合型存在。而出生后12周龄退化期的腔上囊中B细胞内,肌动蛋白则以单体型为主要的存在形式。推测腔上囊B细胞肌动蛋白的聚合程度,可能是与腔上囊B细胞功能状态相关的重要因素之一。

In this study we have examined the state of actin polymerization in B cells from different development stages in bursa of Fabricius of Peking duck by indirect immunofluorescence technique using antibody against actin. In B cells from bursa of Fabricius of 26th day embryo and 3th week after hatching, the polymeric actin was the main form in the actin pool. In B cells from bursa of Fabricius of 12th week after hatching, however, the monomeric actin was the main form, which might be a result of the shift from the polymeric actin pool to the monomeric pool. We concluded that the state of actin polymerization might be an important factor in the cellular functions of B cells of bursa of Fabricius.