家族性息肉病21例诊治分析

Diagnosis and treatment of familial adenomatous polyposis:a report of 21 cases

目的 总结家族性息肉病的临床诊断与治疗经验。方法 对 1985～ 2 0 0 3年 2 1例家族性息肉病病人的诊断与治疗进行回顾性分析。结果 2 1例均行纤维结肠镜检查 ,诊断全结肠及直肠息肉 14例 (6 7% )、直肠及乙状结肠息肉 7例 (33% )。 2 1例均行手术治疗。结论 家族性息肉病有明显的家族史 ,临床以血便为主要表现 ,同时可伴有腹痛、腹泻。纤维结肠镜临床检查可确定诊断。手术是治疗家族性息肉病的首要方法 ,可根据病人的具体情况选择术式。

Objective To summarize the experience in diagnosis and treatment of familial adenomatous polyposis. Methods Diagnosis and treatment of 21 patients with familial adenomatous polyposis admmitted from 1985 to 2003 were retrospectively reviewed.Results All of them were examined with colonofiberscope.Fourteen patients were diagnosed as adenomatous polyposis of colon and rectum ,and 7 patients were diagnosed as adenomatous polyposis of rectum and colon sigmoideum. All of the 21 patients were treated by surgical operations. Conclusion Familial adenomatous polyposis has obvious family history. The common clinical situation is the bloody stool with abdominalgia and diarrhea. The examination with colon of ibroscope is a common method for the patients with the familial adenomatous polyopsis. The surgical operation is the most important treatment for the familial adenomatous polyposis. The operational method should be decided based on patients' condition.