167例系统性红斑狼疮患者的临床及胸部影像学分析

Analysis of clinical and X-ray manifestations in 167 patients with systemic lupus erythematosus

目的 : 分析系统性红斑狼疮 (SLE)患者的临床及胸部影像学改变 ,提高对本病的认识。方法 :分析了 16 7例确诊为SLE患者的临床及胸部X线平片改变 ,包括 2 6例患者的CT片分析。结果 : 16 7例患者中胸部X线异常者 89例 (5 3.3% ) ,主要表现为双肺、心脏、胸膜和膈肌的改变。其中两种或两种以上改变并存者 6 5例 (38.9% )。2 6例胸部CT检查均显示异常。部分影像学改变早于临床表现。结论 : SLE的胸部X线及CT检查对早期胸部病变的诊断有参考价值 ,但由于相对缺乏特异性 。

Objective:To improve clinical recognition on systemic lupus erythematosus (SLE) by analyzing the clinical data and X-ray manifestations of SLE. Methods: Clinical data and X-Ray manifestations of 167 patients with SLE were analyzed retrospectively. Results: Among 167 patients with SLE 89 showed some forms of X-ray abnormalities, mainly demonstrating bilateral changes in lungs, heart, pleura and septal muscle. Of these, combination of two or more than two abnormalities was seen in 65 cases (38.9%). Computerized tomography (CT) abnormalities were also seen in 26 cases. The X-ray manifestations could be the earlier signs than clinical manifestations in some of the cases. Conclusion:X-ray and CT examination can provide a diagnostic clue in some of patients with SLE. However the predictive value is low when used alone in diagnosis of the disease.