500例慢性阻塞性肺疾病诊断规律探讨

Study of Diagnostic Valve in 500 Patients with Chronic Obstrustive Lung Disease

目的 用多元回归分析探讨慢性阻塞性肺疾病 (COPD)诊断的规律性。方法 对 5 0 0例COPD住院病历进行调查 ,记录病人的肺功能、血分析、生化指标 ,采用Spearman相关分析及Liner逐步回归法分析上述指标与诊断的相关性 ,然后对各指标进行两两比较的t检验。结果 诊断的Liner回归得出FEV1(第 1秒用力肺活量 )、C1-(血清氯 )浓度与之负相关 ,NMO(单核、粒细胞百分含量 )与之正相关 ;t检验显示慢性支气管炎、肺气肿、肺心病之间的FEV1、PEF、MEF75、MEF5 0、MEF2 5、NMO值均有显著性差异 ,肺心病与慢支炎、肺气肿二者之间的RDW (红细胞体积分布宽度 )、Na+ 、C1-值有显著性差异。结论 FEV1、PEF、MEF75、MEF5 0、MEF2 5、NMO、RDW、Na+ 。

Objective To explore diagnostic's related factors of chronic obstructive lung disease(COPD).Methods Total cases of 500 that are from clinic were analyzed.To record it's pulmonary function?blood analysis?biochemistry index.Employ correlation analysis and liner multiply regression analysis to analyze the correlation between indexes above-mentioned and diagnosis.Then undertake independent-samples t test.Results Liner regression of diagnosis show that FEV1(forced expiratory volume in first second)?C1 -(chlorine ion density)have negative correlation with diagnosis.NMO(granulocytic cell percentage)has positive correlation with diagnosis.T test show that FEV1?PEF?MEF75?MEF50?MEF25?NMO?RDW have notable difference among chronic bronchitis?emphysema and cor pulmonale.emphysema and cor pulmonale notable difference also demonstrate between emphysema and cor pulmonale with Na + and C1 -.Conclusion It's regarded that FEV1?PEF?MEF75?MEF50?NMO?RDW?Na +?C1 - have better diadynamic value. 〔