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Effects of 24h ultra-marathon on biochemical and hematological parameters 被引量:1

Effects of 24h ultra-marathon on biochemical and hematological parameters
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摘要 AIM: To analyze detailed changes in hematology and biochemistry tests parameters before and after a longdistance race in ultramarathon runners.METHODS: Blood samples of 11 participants were obtained for standard analysis before, immediately after, two days after and nine days after the 2002 International Ultramarathon 24 h Race and the International Association of Ultrarunners (IAU) Asia 24 h Championship.RESULTS: Total bilirubin (BIL-T), direct bilirubin (BIL-D),alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) increased statistically significantly(P<0.05) the race. Significant declines (P<0.05) in red blood cell (RBC), hemoglobin (Hb) and hematocrit (Hct)were detected two days and nine days d after the race.2 d after the race, total protein (TP), concentration of albumin and globulin decreased significantly. While BIL, BIL-D and ALP recovered to their original levels. High-density lipoprotein cholesterol (HDL-C) remained unchanged immediately after the race, but it was significantly decreased on the second and ninth days after the race.CONCLUSION: Ultra-marathon running is associated with a wide range of significant changes in hematological parameters, several of which are injury related. To provide appropriate health care and intervention, the man who receives athletes on high frequent training program high intensity training programs must monitor their liver and gallbladder function. AIM:To analyze detailed changes in hematology and biochemistry tests parameters before and after a long- distance race in ultramarathon runners. METHODS:Blood samples of 11 participants were obtained for standard analysis before,immediately after,two days after and nine days after the 2002 International Ultra- marathon 24 h Race and the International Association of Ultrarunners (IAU) Asia 24 h Championship. RESULTS:Total bilirubin (BIL-T),direct bilirubin (BIL-D), alkaline phosphatase (ALP),aspartate aminotransferase (AST),alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) increased statistically significantly (P<0.05) the race.Significant declines (P<0.05) in red blood cell (RBC),hemoglobin (Hb) and hematocrit (Hct) were detected two days and nine days d after the race. 2 d after the race,total protein (TP),concentration of albumin and globulin decreased significantly.While BIL,BIL-D and ALP recovered to their original levels.High-density lipoprotein cholesterol (HDL-C) remained unchanged immediately after the race,but it was significantly decreased on the second and ninth days after the race. CONCLUSION:Ultra-marathon running is associated with a wide range of significant changes in hematological parameters,several of which are injury related.To provide appropriate health care and intervention,the man who receives athletes on high frequent training program high intensity training programs must monitor their liver and gallbladder function.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第18期2711-2714,共4页 世界胃肠病学杂志(英文版)
基金 Supported by the National Science Council of Taiwan,NSC91-2413-H-159-001
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  • 1Hong-Wei Yao Jun Li Yong Jin Yun-Fang Zhang Chang-Yu Li Shu-Yun Xu Institute of Clinical Pharmacology, Anhui Medical University, Heifei 230032, Anhui Province, China,School of Pharmacy, Anhui Medical University, Heifei 230032, Anhui Province, China.Effect of leflunomide on immunological liver injury in mice[J].World Journal of Gastroenterology,2003,9(2):320-323. 被引量:9

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