Design and Synthesis of Novel Molecular Tweezers Derived from Chenodeoxycholic Acid

Design and Synthesis of Novel Molecular Tweezers Derived from Chenodeoxycholic Acid

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摘要 A novel type of chiral molecular tweezers has been designed and synthesized by using chenodeoxy cholic acid as spacer and the aromatic compounds as arm. Their structures were characterized by 1HNMR, IR, MS spectra and elemental analysis. These chiral molecular tweezers showed good enantioselectivity for D-amino acid methyl esters. A novel type of chiral molecular tweezers has been designed and synthesized by using chenodeoxy cholic acid as spacer and the aromatic compounds as arm. Their structures were characterized by 1HNMR, IR, MS spectra and elemental analysis. These chiral molecular tweezers showed good enantioselectivity for D-amino acid methyl esters.

作者 ZhiGangZHAO QiMingMU ShuHuaCHEN

机构地区 TheFacultyofChemistry

出处《Chinese Chemical Letters》 SCIE CAS CSCD 2004年第11期1285-1288,共4页 中国化学快报（英文版）

关键词 Molecular tweezers SYNTHESIS chenodeoxycholic acid recognition. Molecular tweezers, synthesis, chenodeoxycholic acid, recognition.

分类号 O623.736 [理学—有机化学] O641.3 [理学—物理化学]

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Chinese Chemical Letters

2004年第11期

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Design and Synthesis of Novel Molecular Tweezers Derived from Chenodeoxycholic Acid

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