水稻白叶枯病菌致病性分子遗传学基础

Molecular Genetics of Pathogenicity Determinants of Xanthomonas oryzae pv. oryzae

水稻-白叶枯病原菌互作符合基因对基因关系,是研究禾本科植物-病原菌互作的理想模式系统。目前已鉴定和克隆出许多白叶枯病菌致病相关基因。其它革兰氏阴性植物病原细菌致病性分子遗传学和基因组学研究,为揭示水稻白叶枯病菌致病性分子机理提供了丰富的背景知识,其中以发掘TTSS效应分子的研究备受关注。本文将对白叶枯病菌致病性分子机理进行综述,以期为研究水稻-白叶枯病菌互作的功能基因组学提供科学线索。

Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of bacterial blight disease in rice. The Xoo-Rice interaction is consistent with the gene-for-gene hypothesis and is an ideal model system for understanding mechanisms of molecular plant-pathogen interactions. In the last decade, important pathogenicity-related genes of Xoo had been cloned and identified. Genomic bioinformatics of other gram-negative plant bacterial pathogens, including other Xanthomonas species, has facilitated research on molecular pathogenicity determinants of Xoo, especially on mining TTSS (type III secretion system) effectors. A brief review on the current knowledge of the molecular mechanisms of Xoo pathogenicity is made in order to provide a basis for functional genomics of molecular rice-Xoo interactions.Molecular Genetics of Pathogenicity Determinants of Xanthomonas oryzae pv. oryzae CHEN Gong-you, ZOU Li-fang, WANG Xing-ping, XIANG Yong, WANG Jin-sheng (Key Laboratory for Monitoring and Management of Plant Diseases and Insects, Ministry of Agriculture, Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095) Abstract: Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of bacterial blight disease in rice. The Xoo-Rice interaction is consistent with the gene-for-gene hypothesis and is an ideal model system for understanding mechanisms of molecular plant-pathogen interactions. In the last decade, important pathogenicity-related genes of Xoo had been cloned and identified. Genomic bioinformatics of other gram-negative plant bacterial pathogens, including other Xanthomonas species, has facilitated research on molecular pathogenicity determinants of Xoo, especially on mining TTSS (type III secretion system) effectors. A brief review on the current knowledge of the molecular mechanisms of Xoo pathogenicity is made in order to provide a basis for functional genomics of molecular rice-Xoo interactions. Key words: Rice; Xanthomonas oryzae pv. oryzae; Pathogenicity determinant; Hypersensitive response; Type III secretion system