血清胆红素浓度与冠心病的关系

The relationship between the serum concentration of the total bilirubin and coronary heart disease(CHD)

目的探讨血清胆红素浓度与冠心病的关系。方法采用酶法对68例冠心病患者的血清甘油三酯(TG)、胆固(CHOL)高密度胆固醇(HDL-C)水平,钒酸盐氧化法测定血清总胆红素(TBIL)。结果冠心病患者中低胆红素者58例(≤11.9μmol/L),占85,3%,与健康对照组总胆红素浓度存在显著差异(P<0.01)。在冠心病组对TBIL与TG,CHOL,HDL-C的相关性分析无显著相关性(P>0.05)。结论TBIL浓度与CHD存在负相关性,可作为CHD的又一危险因素。

Objective To study the relationship between the low serum concentration of the total bilirubin(TBIL) and coronary heart disease(CHD). Methods serum TG,CHOL,HDL-C were detected in 68 patients with CHD by using enzymatic method and TBIL by vanadate oxidation method. Results 58 patients with low value of total bilirubin in the patients with CHD (≤11.9μmol/L), the percentage was 85.3% (58/68). There was significant difference of total bilirubin between these patients with CHD and normal control (P<0.01). There was no relation between TBIL and any of TG,CHOL,HDL-C (P>0.05) in the patients with CHD. Conclusion The low concentration of TBIL could be regarded as a dangerous facter of CHD.