摘要
用鳖甲粉对裸鼠载人肠癌进行实验性治疗.在给裸鼠接种人肠癌细胞前2周开始按每天16mg/只的剂量混入饲料经口投与,接种35d后肿瘤体积变化与对照组相比差异有显著性(P<0.05),抑瘤率达92.15％,与饮用5 Fu的阳性对照组比较差异无显著性(P>0.05).来发现鳖甲粉对小鼠产生明显毒性.实验前后白细胞计数与对照组比较差异无显著性.
Nude mice with human rectal adenocarcinoma were treated by turtle's carapace powder. A dose of 16 mg
per mouse every day was given orally 2 weeks prior to tumor trasplantation. It was found that tumor growth
inhibiting rate was 92.15％ at the 35th day after tumor trasplatation, which was significantly different from
the control group. There was significant difference on increasing tumor volume between turtle's carapace
powder group with control group(P<0.05). but no differene with 5 Fu group (P>0.05). No marked toxic
effect was found in turtle's carapace powder group. The white blood cell number was not significantly low-
ered as compared with the negative control group (P<0.05).
出处
《科技通报》
1993年第2期104-107,共4页
Bulletin of Science and Technology
关键词
直肠腺癌
鳖甲粉
裸鼠
rectal adenocarcinoma
turtle's carapace powder
experimental therapy
nude mice
