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妊高征患者cTnT、Myo测定的临床意义 被引量:5

Detection of serum cTnT and Myo in patients with PIH
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摘要 目的 :探讨监测妊娠高血压综合征患者心肌损伤的实验室量化指标。方法 :连续 5 d采用电化学发光技术检测 63例妊高征患者血清肌钙蛋白 T( c Tn T)及肌红蛋白( Myo)的含量。结果 :重度妊高征患者 c Tn T、Myo异常检出率分别为 66.6%和 44.4% ,明显高于轻、中度妊高征组及正常妊娠组 ,差异有显著性 ( P<0 .0 5 ) ;c Tn T虽上升时间较Myo略晚 ,但上升的幅度更大、持续的时间更长。结论 :重度妊高征患者极易发生心肌细胞受损 ,通过有效的实验室指标可以及早发现、监测病情、积极治疗 ,从而改善母婴预后。 Objective: To study the experimental index to inspect myocardio impairment in Pregnancy Induced Hypertension syndrome (PIH) patients. Methods: For 5 days, we determined the serum content of cTnT and Myo in 63 PIH patients by ECL technique. Results: The obnormal rate of cTnT and Myo in severe PIH were 66.6% and 44.4%. Compared with the women of low-grade PIH, middling PIH and normal pregnancy, the rates were much higher (P<0.05). The risetime of cTnT was a little later, but its extent was greater, and the time more longer. Conclusion: The myocardio impairment is incidental in severe PIH patients. With effective experimental index, we can detect early, inspect state of an illness and treat actively, so as to improve the prognosis of the maternity and infant.
出处 《陕西医学杂志》 CAS 北大核心 2004年第11期980-981,共2页 Shaanxi Medical Journal
基金 江苏省常州市科研项目 (编号 :CS2 0 0 3 2 1 2 )
关键词 妊高征 CTNT MYO 测定 肌钙蛋白 肌红蛋白 Pregnancy complication Hypertension Myocardio/injure Cardiac troponin/analysis Myoglobin/analysis
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参考文献2

  • 1Wu A H B. Biochemical markers of cardiac damage:from traditional enzymes to cardiac-specific protein.Scand J Clin Lab Invest, 1999;59 : 74
  • 2Katus HA, Remppis A, Neumann FJ, et al.Diagnostic efficiency of troponin Tmeasurement in Acute myocardial in faiactlon. Clinchem. 1991;83:902

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