急性缺血性脑卒中择时治疗32例临床研究

Clinical Study on Treatment of 32 Cases of Acute Ischemic Apoplexy at Selected Time

目的:观察择时治疗急性缺血性脑卒中的疗效及血液流变学指标的改善情况。方法:将58例急性缺血性脑卒中病人随机分为择时治疗组(观察组)和不择时治疗组(对照组),观察组选择每日辰时(上午7～9时)应用艾条灸足三里穴,配以神阙穴,每日灸1次,每次每穴20分钟,配合中药通络汤,每日1剂,辰时一次性温服。对照组除辰时以外随意选择时间治疗,其治疗方法与观察组相同。两组均3个疗程后评价疗效。两组患者均在治疗前后分别检测血液流变学各项指标以对照观察。结果:观察组痊愈率、显效率显著优于对照组(P<0.01)。两组病人治疗前后血液流变学指标均有所改善,观察组治疗后各项指标的改善程度均具有统计学意义(P<0.05或P<0.01),观察组治疗后与对照组比较,除血浆比粘度、血沉外,其它各项指标均明显优于对照组,差异有显著性(P<0.01)。结论:选择适当的治疗时间,符合现代时间治疗学观点,同样的治疗方法下,可明显提高疗效,值得进一步探讨。

Objective: To observe the therapeutic effect of treatment at selected time on acute ischemic apoplexy and changes of hemorheologic indexes. Methods: 58 cases of acute ischemic apoplexy were randomly divided into a group of treatment at selected time (observation group) and a group of treatment at any time (control group). The observation group were treated by moxibustion at Zusanli (ST 36)and Shenque (CV 8)at Chen hours (7-9 o'clock am)each day, 20min each session, in combination with Chinese drugs Tongluo Decoction, one dose daily, oral administration, once at Chen hours. The control group were treated by the same methods at any hours except Chen hours. The therapeutic effects were assessed after 3 treatment courses. Hemorheologic indexes were determined before and after treatment in both groups. Results: The cured rate and the markedly effective rate in the observation group were better than those in the control group (P<0. 01). The hemorheologic indexes in the two groups after treatment had some improvements with statistically significant differences in the observation group (P<0. 05 or P<0. 01), and the observation group being superior to the control group after treatment (P<0. 01). Conclusion: Selection of suitable therapeutic time conforms to view point of modern time therapeutics and can increase therapeutic effect.