腹膜透析治疗老年慢性肾衰竭的临床研究

Clinical study on peritoneal dialysis in the elderly patients with chronic renal failure

目的:研究腹膜透析和促红细胞生成素等综合治疗老年慢性肾衰竭贫血的效果。方法:对41例(60～82岁)慢性肾衰竭患者,进行了前瞻性的治疗研究,应用腹膜透析、重组人红细胞生成素注射液、益比奥(rHuEPO)2000～3000IU,每周2次或3次皮下注射或10000IU皮下注射,以后参考效果调整剂量。结果:经过腹膜透析与rHuEPO治疗后患者病情明显好转,食欲普遍增进,体力增强,血象均显著升高,肾功能明显好转。结论:腹膜透析与重组人红细胞生成素益比奥等综合治疗老年慢性肾衰竭能取得满意的疗效。

Objective:To study the result of peritoneal dialysis in the elderly patients with chronic renal failure.Methods:A prospective observational study was conducted.Forty-one patients,aged 60 to 82 years,were investigated.The dosage of rHuEPO was 2000IU～3000IU time,2～3time/week or 10000IU a time/week.Results:Recommendation regarding type of peritoneal dialysis must be individualized.After rHuEPO and peritoneal dialysis treatment,BUN、Scr were decreased and CO2CP and Hb increased significantly(P<0.001).Conclusion:Appropriate peritoneal dialysis and rHuEPO treatment show a relatively good therapeutic effect for elderly patients with chronic renal failure.