早产胎膜早破的临床治疗

Clinical therapy of preterm premature rupture of fetal membranes

目的:探讨早产胎膜早破的临床治疗。方法:对232例早产胎膜早破的孕妇资料进行回顾性分析。结果:<34周孕组围生儿死亡率及呼吸窘迫综合征(RDS)发生率(20.8%和15.6%)明显高于≥34周孕组(1.9%和1.3%);而在<34周孕组中,保胎≥48小时后出现的新生儿死亡率及RDS发生率(8.8%和7.0%)较保胎<48小时者(38.5%和28.2%)明显下降。结论:早产胎膜早破期待治疗应当因人施治,对于孕周小者,应尽量延长妊娠至孕34周以上,以降低新生儿的死亡率。

Objective:To discuss the clinical therapy of preterm premature rupture of fetal mebranes.Methods:The clinical data in 232 premature parturients with premature rupture of fetal membranes were analysed retrospectively.Results:The mortality and the occurrence rate of respiratory distress syndrome(RDS) in the perinatal neonates<34 weeks of pregnancy were 20.8%and 15.6%respectively,which were obviously higher than 1.9%and 1.3%in the perinatal neonates≥34 weeks of pregnancy.However,in the perinatal neonates<34 weeks of pregnancy,the mortality and the occurrence rate of RDS in the neonates by protecting fetus≥48 hours were 8.8%and 7.0%respectively,which were obviously reduced comparing to 38.5%and 28.2%in the neonates by protecting fetus<48 hours.Conclusion:Management scheme of preterm premature rupture of fetal membranes should depend on the condition of the patients.The patients with small week pregnoncy should be prolonged to more than 34 weeks of pregnancy as for as possible,so as to reduce the mortality of neonate