顽固性癫痫致痫灶的定位和手术切除分析

LOCALIZATON AND SURGICAL RESECTION OF INTRACTABLE EPILEPTIC FOCI

目的:探讨顽固性癫痫的手术治疗适应证和手术方法的选择。方法:术前应用多导联常规脑电图,术中使用皮层电极和深部电极脑电图明确痫性放电的部位及范围,手术方式有癫痫病灶切除,MST(多处软膜下横切)以及胼胝体前部切开。结果:本组病例共29例,术后无癫痫发作27例,其中12例仍服用少量抗癫痫药物;疗效差或无效2例。结论:严格把握好手术适应证、术前充分准备及合理选用手术方法,是提高顽固性癫痫手术治疗疗效的重要保证。

Objective: To explore the indications and methods of surgical treatment of intractable epilepsies. Method: All the patients underwent scalp EEG, EcoG and depth electrode EEG before surgical treatment including lesionectomy, MST and anterior corpus callosectomy. Results: Of the 29 cases, 27 achieved seizure free after operations, although 12 receiving antiepileptic drugs postoperatively. Conclusion: It is necessary to comply with suitable surgical indication and methods to achieve good seizure control.