离心泵和滚压泵对体外循环术后患者肺功能的影响

Effect of centrifugal and roller pumps on respiratory function following cardiopulmonary bypass

目的 比较应用离心泵和滚压泵的体外循环 (CPB)手术患者术中和术后的肺功能 ,探讨二者对CPB术后患者肺功能的影响。方法 4 0例准备行瓣膜置换手术的患者随机分为两组 (各 2 0例 ) ,在手术时分别应用离心泵和滚压泵作为主泵。在麻醉气管插管后手术开始前、CPB结束后 1小时和即将停用呼吸机拔除气管插管之前三个时点分别抽取桡动脉血立即行血气分析 ,根据 Pa O2 和 Pa CO2 计算肺泡—动脉氧分压差 (Aa DO2 )。结果 两组的 Aa DO2 在三个时点分别比较差异均无显著性 ;组内比较 ,后两个时点与第一时点差异均有显著性。结论 应用离心泵和滚压泵的

Objective To compare the effect of centrifugal and roller pump for cardiopulmonary bypass on respiratory function.Methods 40 patients undergoing cardiac valves replacement were randomly assigned into either centrifugal pump (n=20) or roller pump groups (n=20).Arterial blood gas specimens were sampled to make blood gas analysis after anesthesia and intubation,at 1 hour after cardiopulmonary bypass(CPB) termination and before ventilator weaning and extubation.The PaO 2 and PaCO 2 were used to calculate the alveolar-arterial oxygen difference(AaDO 2).Results There were no significant differences between two groups with time for AaDO 2.But in both groups there was a similar and significant rise in AaDO 2 level when comparing the last two tim-point with baseline values.Conclusion The patients after CPB with centrifugal or roller pump have the same worse respiratory function in terms of gas exchange in operation and in the early postoperative phase.