摘要
目的探讨金属硫蛋白(MT)在宫颈鳞状细胞癌中的表达状况。方法对66例宫颈鳞状细胞癌(CSC)和30例宫颈上皮内瘤样增生(CIN)标本,进行免疫组化检。结果表明 MT在CSC中阳性率为68.18％(45/66),在CIN中阳性率为29.03％(8/30),正常对照组阳性率为8.00％(2/25)。MT表达与癌组织分化程度有关。结论 MT在CSC中有比较高的表达,检测MT对化疗方案制定有指导意义。
Objective To observe expression of MT in cervical squamous cell cancer. Method The MT of 66 cases cervical squamous cell cancer were determined with SP immunohistochemical method. Result The positive rate of MT was 68.18% and 29.03% and 8.00% in cervi- cal squamous cell carcinoma and cervical intraepithelial meoplasia and normal group respectively. There was association between MT expression and cancer differentiation degree. Conclusion MT expression was higher in cervical squamous cell cancer. the MT was determined in carcinoma , that can be significance to direct lay down chemistry scheme.
出处
《医学研究通讯》
2004年第11期48-49,共2页
Bulletin of Medical Research
关键词
金属硫蛋白
宫颈癌
蛋白表达
免疫组化
Metallothionein
Cervical squamous cell carcinoma
Immunohistochemistry
Cervical intraepithelial meoplasia
