运动预防肿瘤发生机制的研究进展

Study on the Mechanism of Preventing Cancer by Physical Activity

许多流行病学的研究都显示运动能减少肿瘤发生的风险。虽然其作用机理并不完全清楚,但是运动可能通过影响性激素、胰岛素及胰岛素样生长因子的分泌,调整免疫,增加自由基的清除,改变体脂的组成及直接抑制肿瘤等方式发挥作用。体育工作者在肿瘤的预防中起着重要的作用。

Epidemiological studies report that regular physical activity can reduce the risk for cancer development. The mechanisms that underlied cancer inhibition with increased physical activity remains unknown. Potential mechanisms influenced by exercise include alternation in sex hormones or insulin/ insulin-like growth factors, immune modulation, alternations in free radical generation, changes in body composition or weight, and direct effects on the tumor. Exercise scientists may play an important role in cancer control efforts at the clinical and population levels.