沙门氏菌食物中毒心肌酶谱和心电图的改变

Changes in myocardial enzyme spectrum and electrocardiogram after Salmonella food poisoning

目的观察分析沙门氏菌食物中毒后的心肌酶和心电图(ECG)的改变.方法对56例沙门氏菌食物中毒患者行心肌酶及ECG检测,同时检测34例正常人作对照.结果病例组在发病2d内有36例(64.29%)心肌酶活性增高;在发病l～4d内,有33例(58.93%)ECG异常,较对照组的肌酸磷酸激酶(CPK)、α-羟基丁酸脱氢酶(α-HBDH)水平显著增高(P＜0.01).结论对沙门氏菌食物中毒患者常规行心肌酶及ECG检查,有助于了解早期心肌酶及ECG改变的情况,以便指导临床用药.

Objective To study the changes in myocardial enzyme spectrum in relation to electrocardiogram (ECG) in Salmonella food poisoning. Methods The myocardial enzyme spectrum and ECG of 56 patients with Salmonella food poisoning were examined, with 34 normal subjects serving as the control group. Results In the food poisoning group, the myocardial enzyme activities was increased in 36 cases (64.29%) within 2 days after the poisoning and the ECG of 33 cases (58.93%) showed abnormal changes within 1-4 days. The levels of creatine phosphoskinase (CPK) and α-hydroxybutyrate acid dehydrogenase (α-HBDH) in poisoning group were obviously higher than those in the control group (P<0.01). Conclusion Routine examination of myocardial enzyme spectrum and ECG helps define early changes in patients with Salmonella food poisoning for clinical treatment decision.