快速冷却灭菌器灭菌乳酸环丙沙星注射液产生沉淀原因的探讨

Reasons for precipitation in ciprofloxation lactate injection sterilized in quick cooling vapor sterilization cabinet

目的 探讨快速冷却灭菌器灭菌乳酸环丙沙星注射液产生沉淀的原因。方法 快速冷却灭菌器与卧式矩形压力蒸汽灭菌器(自然冷却灭菌器)灭菌乳酸环丙沙星注射液对照试验。结果 快速冷却灭菌器灭菌使乳酸环丙沙星注射液析出白色晶型沉淀物。结论 乳酸环丙沙星注射液不宜采用快速冷却灭菌器灭菌,宜用自然冷却灭菌器灭菌。

OBJECTIVE To determine the reasons for the precipitation in ciprofloxtation lactate injection sterilized in quick cooling vapor sterilization cabinet. METHODS Sterilized ciprofloxation lactate injection in quick cooling vapor sterilization cabinet was compared with that in the horizontal rectangle vapor sterilization cabinet. RESULTS The white crystalline precipitates were separated from ciprofloxtation lactate injection sterilized in quick cooling sterilization cabinet. CONCLUSIONS The method of sterilization in the horizontal rectangle vapor sterilization cabinet is more appropriate for ciprofloxation lactate injection than in quick cooling sterilization cabinet.