摘要
To find out the protective polypeptide epitopes of HCV HVR1, the antigenicity of the synthetic peptide was predicted by computer modeling and verified by ELISA and lymphocyte transformation test. It was found that the outcome of the computer modeling was in accord with the experimental results. The method by using computer modeling would be a economic approach by which the protective peptides could be identified quickly.
To find out the protective polypeptide epitopes of HCV HVR1, the antigenicity of the synthetic peptide was predicted by computer modeling and verified by ELISA and lymphocyte transformation test. It was found that the outcome of the computer modeling was in accord with the experimental results. The method by using computer modeling would be a economic approach by which the protective peptides could be identified quickly.
基金
This study was supported by 95 military program ( No. 96M174
98Z089)
