综合治疗强迫症的临床疗效分析

Comparative Study of Cognitive Therapy on Obsessional Compulsive Disorder

目的 :探讨认知疗法在强迫症治疗中的作用及有效性。方法 :将 4 7例强迫症患者分成两组 ,分别用认知疗法合并帕罗西汀 (2 5例为研究组 )和单用帕罗西汀 (2 2例为对照组 )治疗 ,于入组时、治疗 8周后、 6月后分别用 HAMA量表、Y- BOCS量表评定病人 ,并于治疗 6月后用 SDSS量表评定病人。结果 :研究组治疗 8周至 6月后 ,病人 HAMA量表 (6周时 ,t=2 .13,P<0 .0 5 )、Y- BOCS量表总分均显著低于单一用药组 (8周时 t=3.7,P<0 .0 1,6个月时 t=4 .3,P<0 .0 1) ,6月后的 SDSS评分也显著低于对照组(其中总分 t=2 .7,P<0 .0 5 ,职业和工作因子 t=3.3,P<0 .0 1)。结论 :认知疗法可以有效减轻强迫症状 ,改善患者焦虑症状 ,而且对增强社会功能 ,提高生活质量均有较好的效果。

Objective: To explore the effect of cognitive therapy on obsessional compulsive disorder (OCD). Method: Forty-seven patients with OCDO were randomly assigned to cognitive therapy group and conventional treatment group, the later with paroxetine treatment only as control. The results were assessed with Hamilton anxiety scale (HAMA), Yale-Brown Obsessional Compulsive Scale and social disability screening scale. Result: The cognitive therapy group had lower scores in HAMA and Y-BOCS than the control group after 8 weeks therapy, this difference remained in the follow-up after 6 months, when the cognitive group had also lower score in social disability. Conclusion: Cognitive therapy can benefit patients with OCD more than medication only.