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化学发光免疫分析 被引量:35

Chemiluminescence Immunoassay
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摘要 本文综述了化学发光免疫分析的基本原理及应用。根据标记物的不同 ,化学发光免疫分析主要分为三大类 :化学发光免疫分析 ,化学发光酶免疫分析和电化学发光免疫分析。引用文献 89篇。 The principles and applications of chemiluminescence immunoassay are reviewed. According to the kinds of label: three classes of chemiluminescence immunoassay were described. 89 Papers were cited.
出处 《世界科技研究与发展》 CSCD 2004年第4期24-33,共10页 World Sci-Tech R&D
基金 国家杰出青年科学基金项目 (No .2 0 12 5 5 14 )
关键词 电化学发光免疫分析 标记物 酶免疫分析 综述 基本原理 引用文献 根据 应用 chemiluminescence immunoassay, chemiluminescence enzyme immunoassay, electrochemiluminescence immunoassay
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参考文献85

  • 1John W. Leidy, Jr. High sensitivity two-site immunoradiometric andimmunochemiluminometric assays for rat-growth hormone-releasing hormone. Development of acridinium ester based chemiluminescence assays for the avidin-coated bead system. J. Immunol.Methods
  • 2Towbin, H., Schmitz. A., Vanoostrum J., Seitz M., Dewald B. , Zingel O. , Motz J. , Vosbeck K. , Rordorf C. Monoclonal antibody based enzyme-linked and chemiluminescence assays for the human interleukin-1 receptor antagonist application to measure hIL1ra
  • 3Thorpe G H., Kricka L J., Gillespie E., Moseley S., Amess R.,Baggett N. , Whitehead T P. Enhanced of the horseradish peroxidase-catalyzed chemiluminescent oxidation of cyclic diacyl hydrazides by 6-hydroxybenzothiazoles. Anal. Biochem., 1985,145: 96~ 100
  • 4Blackburn G F. , Shah H P. , Kenten J H. , Leland J. , Kamin R A., Link J., Peterman J., Powell M J., Shah A., Talley D B.Electrochemiluminescence detection for development of immunoassays and DNA probe assays for clinical diagnostics. Clin. Chem.,1991, 3
  • 5Van Ingen H E. , Chan D W. , Hubl W., Miyachi H., Molina R., Pitzel L., Ruibal A., Rymer J C. and Domke I., Huub E.Analytical and clinical evaluation of an electrochemiluminescence immunoassay for the determination of CA 125, Clin. Chem.,1998, 44(12): 253
  • 6Namba Y. , Sawada T. , Suzuki O. Development of highly sensitive Ru-Chelate based ECL immunoassay 2: Electrochemical and immunochemical studies on homogeneous and heterogeneous ECL excitation, Anal. Sci., 2000, 16(7): 757~763
  • 7Sanchez-Carbayo M., Espasa A., Chinchilla V., Herrero E.,Megias J. , Mira A. Soria F. New electrochemiluminescent immunoassay for the determination of CYFRA 21-1: analytical evaluation and clinical diagnostic performance in urine samples of patients with
  • 8Thorpe G H. , Bronstein I. , Kricka L J. , Euwards B. , Voyta J C. chemiluminescence enzyme immunoassay of alpha-fetoprotein based on an adamantly dioxetane phenylphosphate substrate. Clin.Chem., 1989, 35:2319~2321
  • 9Marta, S-C., Sanchez-C. , Montserrat M., Rocio A., Carmen M., Federico S. Analytical and clinical evaluation of TSH and thyroid hormones by electrochemiluminescent immunosssays. Clin.Biochem. , 1999, 32(6) :395~403
  • 10Obenauer K. , Linda J. , Jacobs S J. , Karen K. , Tobias L. , Bordens R W. A highly sensitive electrochemiluminescence immunoassay for interferon alfa-2b in human serum. J. Immunol. Methods. , 1997, 206(1-2) :25~33

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