摘要
本文选用青紫蓝家兔25只,分成5组,在复制肠粘连模型的同时,分别于腹腔内注入秋水仙碱,尿激酶,中分子右旋糖酐,秋水仙碱+尿激酶组及生理盐水(对照组)后观察。结果表明,尿激酶组及联合药物组减少了Ⅱ、Ⅲ级粘连的发生。同对照组比较有显著性差异(P<0.01),所运用药物不影响动物生理机能。
Prevention of postoperative reformation of peritoneal adhesions always poses a problem to a surgeon. 25 rabbits were tested,and separated into 5 groups. After reconstructing the animal model of the intestinal adhesions, the peritoneums were injected respectively coclchicine, urokinasum,dextran70, physiological saline and combined therapy with colchicine, urokinasum. The results showed that combined therapy and urokinasum could reduce Ⅱ,Ⅲ grade adhesions reformation of peritoneum significantly. There were much different(P<0.01)comparaed to individual use of the physiological saline. Moreover, all drugs don't affect the physical function of the animals.
出处
《兰州医学院学报》
1993年第1期4-5,8,共3页
Journal of Lanzhou Medical College
关键词
肠粘连
药物预防
实验
Intestinal adhesion Drug prevention
