部分性脾动脉栓塞对肝硬化门静脉高压血流动力学的影响

Effect of partial splenic arterial embolization on hemodynamic in patients with portal hypertension

目的 :探讨部分性脾动脉栓塞术对肝硬化门静脉高压血流动力学的影响。方法 :3 2例肝硬化门静脉高压症患者行部分性脾动脉栓塞治疗 ,在治疗前后 ,应用彩色多普勒超声观察 ,对门静脉 ,脾动、静脉血流动力学变化做定量分析和对比。结果 :部分性脾动脉栓塞术后 4周的门静脉、脾静脉和脾动脉的内径较术前明显缩小 (P <0 .0 1) ,血流量明显减少 (P <0 .0 1) ,血流速度无明显变化 (P >0 .0 5 )。结论 :部分性脾动脉栓塞对肝硬化门静脉高压血流动力学有重要影响 ,可显著降低门静脉压力 。

Objective To assess the effects of partial splenic embolization(PSE) in liver cirrhosis on hemodynamic with portal hypertension.Methods Quantitative analysis and comparative study on portal vein were done,splenic artery and vein hemodynamic changes before and after PSE were studied by color doppler ultrasonography in 32 patients with portal hypertension due to hepatocirrhosis.Results During 4 weeks after the operation,the inner diameters of portal vein,splenic artery and vein were narrowed (P<0.01),the blood flow in aforesaid vessels were reduced (P<0.01) and the velocity of blood flow in these vessels were not changed obviously (P>0.05) compared with those preoperative values.Conclusion PSE is an effective way to reduce the pressure of the portal vein and improve interrelative clinical symptoms significantly.