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人类补体C3研究进展 被引量:26

Advance in researches on the third component of complement(C3)
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摘要 人类补体C3成分是补体激活的经典途径、替代途径以及甘露聚糖结合凝集素 (MBL)途径三者的交汇点 ,是宿主防御机制中占据核心地位的特殊分子。补体C3与其裂解片段构成了人类补体系统的基础框架。现就近年来补体C3基因、蛋白。
出处 《国外医学(临床生物化学与检验学分册)》 2004年第6期519-521,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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  • 1Sahu A, Lambris JD. Structure and biology of complement protein C3,a connecting link between innate and acquired immunity. Immunol Rev, 2001, 180: 35-48.
  • 2Lambris JD, Reid KB, Volanakis JE. The evolution,structure,biology and pathophysiology of complement. Immunol Today, 1999, 20(5): 207-211.
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  • 6Negi VS, Aggarwal A, Dayal R, et al. Complement degradation product C3d in urine: marker of lupus nephritis. J Rheumatol, 2000, 27(2): 380-383.
  • 7Ross TM, Xu Y, Bright RA, et al. C3d enhancement of antibodies to hemagglutinin accelerates protection against influenza virus challenge. Nat Immunol, 2000, 1(2): 127-131.
  • 8Abelseth TK, Stensvag K, Espelid S, et al. The spotted wolffish (Anarhichas minor Olafsen) complement component C3: isolation,characterisation and tissue distribution. Fish Shellfish Immunol, 2003, 15(1): 13-27.
  • 9Sahu A, Morikis D, Lambris JD. Compstatin,a peptide inhibitor of complement,exhibits species-specific binding to complement component C3. Mol Immunol, 2003, 39(10): 557-566.
  • 10Nagar B, Jones RG, Diefenbach RJ, et al. X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2. Science, 1998, 280(5367): 1277-1281.

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