异丁醛缩合法制异丁酸异丁酯

Preparation of Isobutyl Isobutyrate from Isobutyraldehyde by Condensation

依据间歇反应所得一系列数据 ,确定了异丁醛连续缩合反应工艺流程 ;考察了以异丁醛为原料 ,在 5～10℃ ,停留时间 1 5～ 2h ,在异丁氧基铝催化体系作用下 ,两分子异丁醛缩合成一分子异丁酸异丁酯 ;脱除催化剂后 ,粗产品精制得到纯度≥ 99 5 %的异丁酸异丁酯 ,异丁醛的转化率≥ 98 5 % ,异丁酸异丁酯的选择性≥95 %。

In this work,isobutyl isobutyrate was prepared by the condensation of two molecular isobutyraldehyde in the presence of aluminium isobutoxide catalyst system.A process of two serial reactors was confirmed by a series of data from intermittent reactions.The results show that the conditions of 5～10 ℃ of reaction temperature and reaction time 1～2 h are suitable for the reaction. Isobutyl isobutyrate with purity of ≥99.5% was obtained by distillation of the raw product,with the conversion of isobutyraldehyde of≥98.5% and the selectivity to isobutyl isobutyrate of ≥95% respectively.